Dapoxetine vs Paroxetine: Effectiveness for Treating Premature Ejaculation

Premature ejaculation (abbreviated PE) causes severe discomfort and bullying from others. This problem can have a greater impact on a man’s life: he can lose self-confidence and can even avoid new relationships with women. There are not many medicines on the market for treating the disease. Dapoxetine and paroxetine are some of the most effective remedies.

Why Does Premature Ejaculation Occur?

Early ejaculation occurs as a result of unwanted secretion of seminal fluid from the urethra due to too rapid launch of the corresponding mechanisms. This may be due to improper production of hormones, which leads to a violation of physiological reactions. Other physiological reasons include prostate diseases, brain dysfunctions, and traumatic brain injuries.

Anxiety arising from trauma experienced in childhood or adolescence sometimes causes psychological trauma. Ultimately, the result of this anxiety may be uncontrolled ejaculation. Other psychological causes include marital problems, extremely rare sexual intercourse, severe irritability, and prolonged sexual abstinence.

dapoxetine premature ejaculation

Dapoxetine for Treating Premature Ejaculation

Dapoxetine-based drug treatment is the only approved specific therapy for the dealing with premature ejaculation. In some countries, it is available for the treatment of early ejaculation in men from 16 to 64 years old. After taking the pill, you should wait two or three hours to get the desired effect. Ideally, it is recommended to swallow it several hours before sex. It affects hormones and neurotransmitters, and thanks to a chain of complex reactions the effect of ejaculation delay is achieved.

Like most pharmaceutical substances, dapoxetine may cause some unwanted effects (headache, vomiting, gastrointestinal upset, dry mouth, etc.).

The drug has a relatively small half-life and is rapidly excreted from the body. In most cases, this prevents the emergence of a destructive dependence on the drug (which is an antidepressant in nature), despite the fact that this risk is typical for most medicines used to treat premature ejaculation.

dapoxetine vs paroxetine

Paroxetine for the Treatment of Rapid Ejaculation

Since dapoxetine is not approved as a medicine in some countries, patients are forced to use antidepressants that have an effect similar to dapoxetine. Of all suitable medications, paroxetine is reported to be the most effective one.

According to a study by C.G. McMahon and K. Touma (1999), paroxetine at a dosage of 20 mg can be an effective tool in the fight against premature ejaculation. The drug also needs to be taken some time before the planned sexual intercourse. The effect may be more pronounced after a period of ‘loading’, that is, daily use of paroxetine, but you can pay an additional price for this in the form of an increased risk of side effects.

The study by E.A. Jannini et al. (2005) showed that the effectiveness of tadalafil in 25 patients with secondary PE associated with erectile dysfunction was 58.2%, but when combined with SSRIs (paroxetine), it increased to 88.9%.

Thus, dapoxetine is a special medication for the treatment of this sexual disorder, therefore, it is potentially a priority. As for paroxetine, it can be used by men who cannot acquire dapoxetine. Also, this drug works well in conjunction with Cialis (tadalafil) in cases where early ejaculation is associated with erectile dysfunction.

A related article: Best Premature Ejaculation Pills on the Market